Alcohols and polyols
- (1)
- (55)
- (343)
- (39)
- (4)
- (8)
- (7)
- (55)
- (3)
- (7)
- (18)
- (1)
- (4)
- (156)
- (1)
- (64)
- (27)
- (14)
- (3)
- (1)
- (1)
- (10)
- (3)
- (2)
- (2)
- (1)
- (1)
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- (1)
- (1)
- (1)
- (6)
- (3)
- (30)
- (4)
- (20)
- (10)
- (2)
- (10)
- (4)
- (5)
- (395)
- (6)
- (102)
- (21)
- (50)
- (31)
- (62)
- (13)
- (14)
- (1)
- (2)
- (1)
- (25)
- (6)
- (4)
- (1)
- (6)
- (1)
- (463)
- (9)
- (46)
- (10)
- (46)
- (6)
- (1)
- (6)
- (12)
- (145)
- (116)
- (7)
- (5)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (7)
- (14)
- (2)
- (1)
- (6)
- (5)
- (1)
- (12)
- (21)
- (5)
- (2)
- (2)
- (2)
- (16)
- (2)
- (30)
- (1)
- (4)
- (1)
- (2)
- (1)
- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (1)
- (2)
- (2)
- (2)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (15)
- (4)
- (5)
- (1)
- (2)
- (5)
- (1)
- (4)
- (37)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (8)
- (7)
- (7)
- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (2)
- (1)
- (15)
- (12)
- (1)
- (2)
- (2)
- (7)
- (12)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (22)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (6)
- (4)
- (1)
- (3)
- (6)
- (11)
- (5)
- (3)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (2)
- (1)
- (3)
- (1)
- (2)
- (1)
- (10)
- (1)
- (2)
- (4)
- (4)
- (1)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (5)
- (4)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (5)
- (1)
- (2)
- (2)
- (6)
- (14)
- (2)
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- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
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- (2)
- (1)
- (1)
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- (2)
- (3)
- (2)
- (4)
- (3)
- (1)
- (4)
- (5)
- (1)
- (4)
- (5)
- (9)
- (1)
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- (5)
- (2)
- (1)
- (1)
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- (3)
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- (1)
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- (2)
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- (1)
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- (1)
- (1)
- (1)
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- (11)
- (1)
- (2)
- (4)
- (20)
- (21)
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- (1)
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- (1)
- (1)
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- (1)
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- (1)
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- (1)
- (1)
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- (1)
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- (1)
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- (1)
- (1)
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- (1)
- (1)
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- (1)
- (1)
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- (1)
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- (1)
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- (1)
- (1)
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- (1)
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- (1)
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- (60)
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- (2)
- (1)
- (1)
- (30)
- (2)
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- (11)
- (82)
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- (1)
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- (7)
- (5)
- (1)
- (81)
- (3)
- (378)
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- (40)
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- (1)
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- (1)
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- (2)
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- (1)
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- (1)
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- (279)
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- (1)
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- (278)
- (28)
- (2)
- (25)
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- (48)
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- (3)
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- (3)
- (1)
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- (21)
- (16)
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- (1)
- (8)
- (2)
- (733)
- (11)
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- (2)
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- (2)
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- (2)
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- (1)
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- (1)
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- (1)
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- (2)
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- (2)
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- (2)
- (1)
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- (1)
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- (2)
- (1)
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- (1)
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- (1)
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- (1)
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Filtered Search Results
Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | >98.0% | 327.89 | C21H26ClN | 200 MG
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Melitracen hydrochloride is a research-grade tricyclic antidepressant hydrochloride salt supplied for laboratory use. It is used in pharmacological studies of monoamine neurotransmitter uptake and serotonergic (5-HT) receptor pathways. Provided as a solid for in vitro and preclinical research; not for human or veterinary use.
- Tricyclic antidepressant hydrochloride salt.
- Molecular formula C21H26ClN.
- Molecular weight 327.89.
- Purity >98.0% (HPLC).
- Available as a solid powder, commonly in 200 MG quantities.
- For research use only; not for human or veterinary use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Azasetron hydrochloride | 123040-16-4 | MFCD00209913 | 99.8% | C17H21Cl2N3O3 | 5 MG
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Azasetron hydrochloride is a benzamide derivative functioning as a potent and selective 5-HT3 receptor antagonist. It is utilized in studies concerning chemotherapy-induced nausea and vomiting (CINV).
- Potent and selective 5-HT3 receptor antagonist
- Used in studies for chemotherapy-induced nausea and vomiting (CINV)
- Purity of 99.76%
- Solid, white to off-white appearance
- Effectively penetrates skin in in vivo studies
- IC50 for 5-HT3 Receptor is 0.33 nM
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Endoxifen hydrochloride | 1197194-41-4 | 98.0% | 409.95 | 5 MG
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Endoxifen hydrochloride is a key active metabolite of Tamoxifen (TAM) with higher affinity and specificity to the estrogen receptor, and it also inhibits aromatase activity. It has potential for breast cancer study.
- Key active metabolite of Tamoxifen (TAM).
- Higher affinity and specificity to estrogen receptor.
- Inhibits aromatase activity.
- Potential for breast cancer study.
- Approximately 100-fold more potent as an antagonist of the ER than tamoxifen.
- Targets estrogen receptor α for degradation in breast cancer cells.
- Blocks ERA transcriptional activity and inhibits estrogen-induced breast cancer cell proliferation.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Imeglimin (hydrochloride) | 775351-61-6 | 99.3% | 191.66 | 50 MG
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Imeglimin hydrochloride (EMD 387008) is an oral glucose-lowering agent. It also reduces reactive oxygen species (ROS) production, increases mitochondrial DNA, and improves mitochondrial function.
- Oral glucose-lowering agent
- Reduces reactive oxygen species production
- Increases mitochondrial DNA
- Improves mitochondrial function
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Medchemexpress LLC Ansofaxine hydrochloride | 916918-84-8 | 417.97 | 25 MG
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Ansofaxine hydrochloride is a triple reuptake inhibitor designed to inhibit serotonin, dopamine, and norepinephrine reuptake. It demonstrates IC50 values of 723 nM, 491 nM, and 763 nM for these reuptake processes, respectively. This compound is intended for research use only.
- Triple reuptake inhibitor
- Inhibits serotonin, dopamine, and norepinephrine reuptake
- Intended for research use only
- Appears as a solid
- Color ranges from white to off-white
- Recommended storage for solid is 4°C, sealed and away from moisture
- For solutions, store at -80°C for up to 6 months, or -20°C for 1 month
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Medchemexpress LLC SSR180711 hydrochloride | 446031-79-4 | 99.90% | 361.66 | 1 ML
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SSR180711 hydrochloride is an orally active, selective, and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. It can act on rat α7 n-AChR (Ki=22 nM; IC50=30 nM) and human α7 n-AChR (Ki=14 nM; IC50=18 nM). This compound increases glutamatergic neurotransmission, ACh release, and long-term potentiation (LTP) in the hippocampus.
- Acts on rat α7 n-AChR (Ki=22 nM; IC50=30 nM) and human α7 n-AChR (Ki=14 nM; IC50=18 nM).
- Increases glutamatergic neurotransmission, ACh release, and long-term potentiation (LTP) in the hippocampus.
- Selective for the α7 receptor subtype compared to α4β2, α3β2, α3β4, and α1β1γδ human n-AChR subtypes.
- Rapidly penetrates into the brain (ID50=8 mg/kg; p.o.).
- Dose-dependently inhibits specific [3H]α-BTX binding in the mouse brain.
- Dose-dependently increases extracellular acetylcholine (ACh) levels in the hippocampus and prefrontal cortex of freely moving rats.
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Medchemexpress LLC Emixustat hydrochloride | 1141934-97-5 | MFCD28400873 | 99.3% | 299.84 | C16H26ClNO2 | 10 MG
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Emixustat hydrochloride is a research-grade RPE65 inhibitor and visual cycle modulator used to study retinal physiology and degenerative eye diseases. It inhibits retinol isomerization with low-nanomolar potency (IC50 ~4.4 nM) and is supplied as a hydrochloride salt for stability; it is used in both in vitro and in vivo retinal research models.
- Inhibits RPE65 with low-nanomolar potency.
- Modulates the visual cycle to reduce retinol isomerization.
- Suitable for in vitro and in vivo retinal research applications.
- Supplied as a hydrochloride salt for improved handling and stability.
- High purity by LCMS (reported >99%).
- Available in small-mass packaging for dosing and preclinical studies.
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Medchemexpress LLC Aprindine hydrochloride | 33237-74-0 | 99.0% | C22H31ClN2 | 50 MG
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Aprindine hydrochloride is an Ib-class anti-arrhythmic agent. It primarily blocks sodium channels (INa) and significantly inhibits delayed potassium currents, helping to prolong the atrial effective refractory period (AERP) and prevent atrial fibrillation. It also regulates intracellular calcium ion concentration by inhibiting the Na+/Ca2+ exchange current (INCX), further stabilizing cardiac electrical activity. It is used in the study of atrial fibrillation (AF) and ventricular arrhythmias.
- Functions as an Ib-class anti-arrhythmic agent.
- Blocks sodium channels (INa) and inhibits delayed potassium currents.
- Regulates intracellular calcium ion concentration by inhibiting Na+/Ca2+ exchange current (INCX).
- Used for studying atrial fibrillation (AF) and ventricular arrhythmias.
- Inhibits proliferation of bone marrow cells and human lymphocytes.
- Demonstrates anti-arrhythmic effects in vivo.
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Medchemexpress LLC Prasugrel hydrochloride | 389574-19-0 | C20H21ClFNO3S | 500 MG
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Prasugrel hydrochloride (PCR 4099 hydrochloride) is a thienopyridine and a proagent that inhibits platelet function. It is an orally active and potent P2Y12 receptor antagonist, which works by inhibiting ADP-induced platelet aggregation. In rat platelets, the active metabolite of Prasugrel hydrochloride inhibits in vitro platelet aggregation induced by adenosine ADP (10μM) with an IC50 value of 1.8 μM.
- Exhibits faster and significantly more potent antiplatelet effects in vivo compared to Clopidogrel.
- Requires in vivo metabolic processing as an inactive prodrug to generate its active antiplatelet metabolite.
- Rapidly absorbed from the gut following oral administration.
- Achieves maximum plasma levels of active metabolite within 1 hour.
- Leads to effective, maximum inhibition of platelet aggregation within 1-2 hours.
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Medchemexpress LLC Fedratinib (hydrochloride hydrate) | 1374744-69-0 | MFCD28137677 | 99.9% | 615.62 g/mol | C27H40Cl2N6O4S | 2 G
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Fedratinib hydrochloride hydrate is the dihydrochloride monohydrate salt of fedratinib, an ATP-competitive, orally active and selective JAK2 inhibitor supplied for research use. The compound is provided as a solid (white to yellow) with high reported purity and is intended for in vitro and preclinical studies; not for human therapeutic use.
- High purity (≈99.9%) as reported by supplier.
- Molecular weight 615.62 g/mol; formula C27H40Cl2N6O4S.
- Packaged in small-scale quantities, commonly available as 2 G.
- Recommended storage: solid at 4°C; in solution -20°C to -80°C.
- Potent JAK2 inhibitor with reported IC50 ≈3 nM, suitable for signaling and oncology research.
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Medchemexpress LLC SB-612111 hydrochloride | 371980-94-8 | 99.6% | 454.86 | 25 MG
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SB-612111 hydrochloride is a novel and potent opiate receptor-like orphan receptor (ORL-1) antagonist. It demonstrates high affinity for hORL-1 and selectivity for μ-, κ- and δ-receptors. This compound effectively antagonizes the pronociceptive action of Nociceptin in acute pain models.
- Potent opiate receptor-like orphan receptor (ORL-1) antagonist
- High affinity for hORL-1 (Ki=0.33 nM)
- Exhibits selectivity for μ-, κ- and δ-receptors
- Antagonizes pronociceptive action of Nociceptin
- Had antihyperalgesic effects on carrageenan-induced rat paw
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Medchemexpress LLC Etifoxine hydrochloride | 56776-32-0 | MFCD00868190 | 99.9% | 337.24 g·mol⁻¹ | C17H18Cl2N2O | 10 MG
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Etifoxine hydrochloride is a non-benzodiazepine GABAergic compound used in research to modulate GABAA receptor activity. It is supplied as the hydrochloride salt for improved handling and solubility, and is commonly used in preclinical studies of anxiolytic and anticonvulsant effects.
- Acts as a positive allosteric modulator of GABAA receptors
- Hydrochloride salt form for enhanced solubility
- High purity suitable for research applications
- Available in small research pack sizes for preclinical work
- Used in studies of anxiolytic and anticonvulsant pharmacology
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Medchemexpress LLC Mozavaptan hydrochloride | 138470-70-9 | MFCD11111965 | 99.9% | 464.0 g/mol | C27H30ClN3O2 | 5MG
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Mozavaptan hydrochloride (OPC-31260 hydrochloride) is a benzazepine-derived, potent and selective vasopressin V2 receptor antagonist (reported IC50 ≈14 nM) used as a research chemical for studies of vasopressin signaling and conditions such as hyponatremia and SIADH. It is supplied as a white to off-white solid and is commonly available in small milligram quantities or as a DMSO solution for in vitro and pharmacology experiments. Molecular formula C27H30ClN3O2; molecular weight 464.0 g/mol; CAS 138470-70-9.
- High purity suitable for research (≈99.9%)
- Potent V2 receptor antagonist activity for pharmacology studies
- Available in solid and DMSO solution formats
- Compact packaging for small-scale experiments
- Standard identifiers provided for traceability
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Medchemexpress LLC Leelamine hydrochloride | 16496-99-4 | 98.10% | 321.93 | 1 ML
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Leelamine hydrochloride is a tricyclic diterpene molecule extracted from the bark of pine trees. It acts as a cannabinoid receptor type 1 (CB1) agonist and an inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells, independent of androgen receptor status. It also suppresses the transcriptional activity of the androgen receptor, which regulates fatty acid synthesis.
- Acts as a cannabinoid receptor type 1 (CB1) agonist
- Inhibits SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells
- Suppresses the transcriptional activity of the androgen receptor
- Extracted from the bark of pine trees
- Appears as a white to off-white solid
- Store at -20°C in sealed conditions, away from moisture
- For storage in solvent, store at -80°C for 6 months, or -20°C for 1 month in sealed conditions, away from moisture
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Medchemexpress LLC Imeglimin (hydrochloride) | 775351-61-6 | 99.3% | 191.66 | 25 MG
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Imeglimin hydrochloride (EMD 387008) is an oral glucose-lowering agent that reduces reactive oxygen species (ROS) production, increases mitochondrial DNA, and improves mitochondrial function. This compound appears as a white to off-white solid.
- Oral glucose-lowering agent
- Reduces reactive oxygen species (ROS) production
- Increases mitochondrial DNA
- Improves mitochondrial function
- Soluble in H2O (≥ 50 mg/mL)
- Soluble in DMSO (25 mg/mL)
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