Protein Analysis Reagents
MilliporeSigma™ Calbiochem™ GW1929
A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays).
MilliporeSigma™ Calbiochem™ LIM Kinase Inhibitor I, LIMKi 3
The LIM Kinase Inhibitor I, LIMKi 3 controls the biological activity of LIM Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ mGlu7 Antagonist, XAP044
A blood-brain barrier permeable, potent, selective, and reversible antagonist of mGlu7 receptor (IC50 = 3.5 and 2.8 μM for mGlu7a and mGlu7b in CHO cells).
MilliporeSigma™ Calbiochem™ Adenosine 3',5'-cyclic Monophosphate, N6,O2'-Dibutyryl-, Sodium Salt
This Dibutyryl-cAMP, CAS 16980-89-5, is a cell-permeable cAMP analog that preferentially activates PKA.
MilliporeSigma™ Calbiochem™ Juglone
A highly selective cell-permeable, irreversible inhibitor of PPlases (peptidyl-prolyl cis/trans isomerases of the parvulin family).
MilliporeSigma™ Calbiochem™ STAT5 Inhibitor II, IQDMA
The STAT5 Inhibitor II, IQDMA controls the biological activity of STAT5.
MilliporeSigma™ Calbiochem™ LSD1 Inhibitor II, S2101
The LSD1 Inhibitor II, S2101 controls the biological activity of LSD1. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ Dihydroorotate Dehydrogenase Inhibitor, Brequinar
An immunosuppressive and anti-neoplastic agent that inhibits pyrimidine synthesis by blocking the activity of mammalian mitochondrial dihydroorotate dehydrogenase (DHODH; IC50 = 12 nM).
MilliporeSigma™ Calbiochem™ Leukadherin-1
A furanyl thiazolidinone compound that binds CD11b αA/αI domain in a reversible manner and stabilizes αA in a high-affinity binding conformation toward known CD11b/CD18 (αMβ2; CR3; Mac-1) ligands, fibrinogen, ICAM-1, and iC3B.
MilliporeSigma™ Calbiochem™ JNK Inhibitor I, (L)-Form, Cell-Permeable
The JNK Inhibitor I, (L)-Form, Cell-Permeable controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ p21-Activated Kinase Inhibitor III, IPA-3
The p21-Activated Kinase Inhibitor III, IPA-3, also referenced under CAS 42521-82-4, controls the biological activity of p21-Activated Kinase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ NFAT Inhibitor, MCV1
The NFAT Inhibitor, MCV1 controls the biological activity of NFAT.
MilliporeSigma™ Calbiochem™ TLR8 Agonist, cpd14b
A potent agonist of Toll-like receptor 8 agonist (TLR8, EC50 = 200 nM).
MilliporeSigma™ Calbiochem™ Loperamide Hydrochloride
A very potent and highly selective peripheral resctrictedμ-opioid receptor agonist (Ki = 2
MilliporeSigma™ Calbiochem™ InSolution™ JAK Inhibitor I
The InSolution™ JAK Inhibitor I, also referenced under CAS 457081-03-7, controls the biological activity of JAK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.