Lipids and Lipid Derivatives
Medchemexpress LLC C18-ceramide | 2304-81-6 | MFCD00056222 | 100.0% | 565.95 g/mol | C36H71NO3 | 50 MG
C18-ceramide is a naturally occurring bioactive sphingolipid used in biomedical research to investigate cell signaling, apoptosis, autophagy, and neuronal injury mechanisms. It modulates endoplasmic reticulum stress and PI3K/AKT pathways, can influence exocytosis and lipid-raft functions, and is commonly applied in oncology and neuroscience studies. Supplied for research use only.
- Bioactive sphingolipid involved in apoptosis and autophagy
- Modulates endoplasmic reticulum stress and PI3K/AKT signaling pathways
- Capable of crossing the blood-brain barrier
- High purity (99.95%) suitable for research applications
- Available in multiple package sizes, including 50 mg
- Supplied for research use only; not for human use
Cayman Chemical 11-ProstaglndIn E1 10mg
11β-PGE1 is an epimerized form of PGE1 at the C-11 position. 11β-PGE1 is a less potent isomer of PGE1. It is 13% and 3.6% as potent as PGE1 in contracting the rat uterus and guinea pig ileum, respectively.{4158}
Ambeed RHODIUM II OCTANOATE DIMER 1G
AmBeed / Rhodium II Octanoate Dimer / 1g / A907319 / 98 percent / CAS 73482-96-9 / M.W. 98 percent / MFCD00064724
Medchemexpress LLC AKN-028 (acetate) | 98.4% | 362.39 | 10 MG
AKN-028 acetate is a novel tyrosine kinase (TK) inhibitor and a potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC50 value of 6 nM. It inhibits FLT3 autophosphorylation, induces dose-dependent cytotoxic response (mean IC50=1 μM), and triggers apoptosis by activating caspase 3. This compound is used in research of acute myeloid leukemia (AML).
- Potent, orally active FLT3 inhibitor (IC50 value of 6 nM)
- Inhibits FLT3 and KIT autophosphorylation
- Induces dose-dependent cytotoxic response (mean IC50=1 μM)
- Triggers apoptosis by activating caspase 3
- Effective in research models of acute myeloid leukemia (AML)
- Exhibits cytotoxic activity against AML cell lines
- Targets multiple kinases including CLK1, RPS6KA, VEGFR2, and FGFR2
Medchemexpress LLC Decyl methyl ether | 7289-52-3 | MFCD00216758 | >95.0% | 172.31 g/mol | C11H24O | 100 MG
Decyl methyl ether (1-methoxydecane) is a fatty ether used as a laboratory reagent, solvent, and fragrance ingredient reference. It is supplied in small laboratory packs; consult the certificate of analysis and SDS for lot-specific purity and handling.
- Used as a solvent and biochemical assay reagent.
- Synonym: 1-methoxydecane.
- Chemical formula: C11H24O.
- Molecular weight: 172.31 g/mol.
- Reported purity: >95.0% by GC; consult CoA for lot values.
- Available in small packs suitable for analytical and research use.
Medchemexpress LLC (-)-Bornyl acetate | 5655-61-8 | 196.29 | 10 G
Isolated from hyssop oil, (-)-Bornyl acetate (L-(-)-Bornyl acetate) is an antifungal agent. It is a less active enantiomer of (+)-Bornyl acetate. Wavy roots from seedlings exposed to (-)-bornyl acetate are significantly longer than those from seedlings exposed to (+)-bornyl acetate. When applied individually to barley seedlings, (-)-Bornyl acetate reduced powdery mildew infection compared to controls without ether.
- Isolated from hyssop oil
- Antifungal activity
- Less active enantiomer of (+)-Bornyl acetate
Medchemexpress LLC Larazotide acetate | 881851-50-9 | MFCD31630844 | 99.7% | 785.89 g/mol | C34H59N9O12 | 1 MG
Larazotide acetate is a synthetic peptide zonulin antagonist used in preclinical research to modulate intestinal tight junction permeability. Supplied as a solid powder for laboratory research, it has documented activity in cell-based and animal models affecting barrier function.
- Orally active zonulin antagonist that modulates tight junctions.
- Characterized in cell-based assays and animal models for reducing intestinal permeability.
- High purity (99.68%) suitable for research applications.
- Solid, white to off-white powder for laboratory use.
- Storage: powder stable at -80°C for up to 2 years and -20°C for up to 1 year.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC Prednisolone acetate | 52-21-1 | 99.3% | 250 MG
Prednisolone acetate is an adrenocortical hormone active molecule with various pharmacological effects such as anti-inflammatory, anti-allergic, and immune suppression. This high-purity compound is for research use only and is stable under recommended storage conditions, making it suitable for a wide range of laboratory applications.
- Exhibits anti-inflammatory effects
- Acts as an anti-allergic agent
- Provides immune suppression
- Targets glucocorticoid receptors
- Stable for long-term storage in powder or solvent form
- Ships at room temperature
Apexbio Technology LLC Luteinizing hormone releasing hormone human acetate salt (LHRH) 33515-09-2 1mg
Luteinizing hormone releasing hormone human acetate salt (LHRH) is a neuropeptide hormone targeting anterior pituitary signaling pathways It is designed to stimulate the anterior pituitary gland thereby promoting secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) LHRH exerts its biological activity primarily by selectively activating matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) key enzymes involved in extracellular matrix remodeling In studies with human endometrial cancer cell lines and decidual stromal cells LHRH mediates induction of MMP-9 expression and activation Based on these pharmacological properties LHRH holds research potential in reproductive biology embryo implantation tumor cell invasiveness and metastasis studies
Apexbio Technology LLC Atosiban acetate 914453-95-5 50mg
Atosiban acetate (CAS 914453-95-5) is a synthetic peptide functioning as a dual antagonist of the oxytocin receptor (OTR) and vasopressin receptors (V1aR V1bR V2R) It exhibits high affinity for human OTR (pKi 7 9) and V1aR (pKi 9 8) and effectively inhibits cell proliferation in MDCK and HEK293 cells stably expressing human OTR with IC50 values of 15 4 nM and 20 8 nM respectively In preclinical models Atosiban acetate suppresses uterine contractions and delays preterm labor Its application in research includes studies of receptor-mediated signaling uterine contractility and biased agonism Due to its peptide nature it is not suitable for oral or long-term use
Medchemexpress LLC Alisol A 24-acetate | 18674-16-3 | 98.0% | 532.75 | C32H52O6 | 10 MG
Alisol A 24-acetate is a naturally occurring prototerpene-type triterpenoid supplied as a high-purity research chemical for biochemical and pharmacological studies. It is provided as a solid or as a ready-to-use DMSO solution for assay applications and is intended for research use only.
- high purity: 98.0% by analytical specification
- small-scale quantities suitable for screening and pilot studies
- available as a solid and as a 10 mM solution in DMSO
- molecular formula: C32H52O6; molecular weight: 532.75
- provided with datasheet, certificate of analysis, and safety data sheet
Medchemexpress LLC Ulipristal acetate | 126784-99-4 | 99.9% | 475.62 | 50 MG
Ulipristal acetate (CDB-2914) is an orally active, selective progesterone receptor modulator (SPRM). It stimulates the autophagic response selectively in leiomyoma cells and has the potential for treating benign gynecological conditions such as uterine myoma.
- Orally active, selective progesterone receptor modulator (SPRM).
- Stimulates the autophagic response selectively in leiomyoma cells.
- Potential for benign gynecological conditions treatment, such as uterine myoma.
- Exhibits significant antiprogestational activity in vivo.
- Decreases incidences of fibroadenomas and adenocarcinomas in the mammary gland in all treated groups.
- Increases the frequency with which pathologists assessed the endometrium as being thickened in a dose-dependent manner.
Medchemexpress LLC Farnesyl pyrophosphate (ammonium) | 116057-57-9 | 95.4% | 433.42 | 1 MG
Farnesyl pyrophosphate (ammonium) | 116057-57-9 | 95.4% | 433.42 | 1 MG
Medchemexpress LLC S961 acetate | 99.8% | 4802.12 | 10 MG
S961 acetate is a high-affinity and selective insulin receptor (IR) antagonist with IC50s of 0.048 nM for HIR-A and 0.027 nM for HIR-B. It also exhibits high affinity for Rat IR and Pig IR. This compound is intended for research use only.
- High-affinity and selective insulin receptor (IR) antagonist
- IC50s of 0.048 nM for HIR-A
- IC50s of 0.027 nM for HIR-B
- Also targets human insulin-like growth factor I receptor (HIGF-IR)
- High affinity for rat IR and pig IR
- Chemical formula: C211H295N55O71S2.xC2H4O2
- Appears as a white to off-white solid